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Iron regulation and quorum-sensing system in Pseudomonas aeruginosa
Author(s):
WEI Yang
,
ZHANG Ya-ni
,
DUAN Kang-min
Pages:
828
-
832
Year:
2010
Issue:
5
Journal:
Journal of Northwest University(Natural Science Edition)
Abstract:
目的 分析总结铜绿假单胞菌铁调节机理及其与群体感应系统之间的调节关系.方法 汇总实验室有关铁调节和群体感应系统的研究结果 ,并结合相关文献资料进行分析总结.结果 铜绿假单胞菌可以通过多种途径吸收利用不同来源或状态的铁源,在各种铁吸收途径中以铁载体介导途径尤为重要.Fur蛋白作为调节中心,与小RNA和ECF sigma因子共同对铁平衡进行精巧调节,而铁调节和群体感应系统相互影响,共同调节着相关基因的...
Citations
KOHLER T,DELDEN C V,CURTY L K et al.Overexpression of the MexEF-OprN multidrug efflux system affects cell-to-cell signaling in Pseudomonas aeruginosa[J].J Bacteriol,2001,183(18):5213-5222.
CARTRON M L,MADDOCKS S,GILLINGHAM P,et al.Feo-transport of ferrous iron into bacteria[J].Biometals,2006,19(2):143-157.
LLAMAS M A,SPARRIUS M,KLOET R,et al.The heterologous siderophores ferrioxamine B and ferrichrome activate signaling pathways in Pseudomonas aeruginosa[J].J Bacteriol,2006,188(5):1882-1891.
GHYSELS B,OCHSNER U,MOLLMAN U,et al.The Pseudomonas aeruginosa pirA gene encodes a second receptor for ferrienterobactin and synthetic catecholate analogues[J].FEMS Microbiol Lett,2005,246(2):167-174.
OGLESBY AG,FARROW J M.LEE J H,et al.The influence of iron on Pseudomonas aeruginosa physiology:a regulatory link between iron and quorum sensing[J].J Biol Chem,2008,283(23):15558-15567.
WILDERMAN P J,SOWA N A,FITZGERALD D J,et al.Identification of tandem duplicate regulatory small RNAs in Pseudomonas aeruginosa involved in iron homeostasis[J].Proc Natl Acad Sci U S A,2004,101(26):9792-9797.
LAMONT I L,BEARE P A,OCHSNER U,et al.Siderophore-mediated signaling regulates virulence factor production in Pseudomonasaeruginosa[J].Proc Natl Acad Sci U S A,2002,99(10):7072-7077.
SMITH R S,LGLEWSKI B H.P aeruginosa quorum-sensing systems and virulence[J].Curr Opin Microbiol,2003,6(1):56-60.
JUHAS M,EBERL L,TUMMLER B.Quorum sensing:the power of cooperation in the world of Pseudomonas[J].Environ Microbiol,2005,7(4):459-471.
WITHERS H,SWIFT S,WILLIAMS P.Quorum sensing as an integral component of gene regulatory networks in Gram-negative bacteria[J].Curr Opin Microbiol,2001,4(2):186-193.
KOHLER T,DELDEN C V,CURTY L K et al.Overexpression of the MexEF-OprN multidrug efflux system affects cell-to-cell signaling in Pseudomonas aeruginosa[J].J Bacteriol,2001,183(18):5213-5222.
CARTRON M L,MADDOCKS S,GILLINGHAM P,et al.Feo-transport of ferrous iron into bacteria[J].Biometals,2006,19(2):143-157.
LLAMAS M A,SPARRIUS M,KLOET R,et al.The heterologous siderophores ferrioxamine B and ferrichrome activate signaling pathways in Pseudomonas aeruginosa[J].J Bacteriol,2006,188(5):1882-1891.
GHYSELS B,OCHSNER U,MOLLMAN U,et al.The Pseudomonas aeruginosa pirA gene encodes a second receptor for ferrienterobactin and synthetic catecholate analogues[J].FEMS Microbiol Lett,2005,246(2):167-174.
OGLESBY AG,FARROW J M.LEE J H,et al.The influence of iron on Pseudomonas aeruginosa physiology:a regulatory link between iron and quorum sensing[J].J Biol Chem,2008,283(23):15558-15567.
WILDERMAN P J,SOWA N A,FITZGERALD D J,et al.Identification of tandem duplicate regulatory small RNAs in Pseudomonas aeruginosa involved in iron homeostasis[J].Proc Natl Acad Sci U S A,2004,101(26):9792-9797.
LAMONT I L,BEARE P A,OCHSNER U,et al.Siderophore-mediated signaling regulates virulence factor production in Pseudomonasaeruginosa[J].Proc Natl Acad Sci U S A,2002,99(10):7072-7077.
SMITH R S,LGLEWSKI B H.P aeruginosa quorum-sensing systems and virulence[J].Curr Opin Microbiol,2003,6(1):56-60.
JUHAS M,EBERL L,TUMMLER B.Quorum sensing:the power of cooperation in the world of Pseudomonas[J].Environ Microbiol,2005,7(4):459-471.
WITHERS H,SWIFT S,WILLIAMS P.Quorum sensing as an integral component of gene regulatory networks in Gram-negative bacteria[J].Curr Opin Microbiol,2001,4(2):186-193.
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