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Journal Articles
The Suppression of c-fos in Neuron Apoptosis Induced by Heroin
Pages: 321-324
Year: Issue:  5
Journal: Journal of Forensic Medicine

Abstract: 目的 观察海洛因对SD乳鼠小脑颗粒神经元c-fos蛋白表达的影响,探讨海洛因对神经元的损伤机制.方法 体外培养原代小脑颗粒神经元并建立海洛因促神经元凋亡模型,用逆转录聚合酶链反应(reverse transcription-polymerase chain reaction,RT-PCR)和Western印迹法技术,检测小脑颗粒神经元凋亡时c-fos的表达变化. 结果海洛因质量浓度为10μg/mL...
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