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Relationship between the deletion of GSTM1, GSTT1 genes and susceptibility to malignant of nail matrix naevus
Pages: 1729-1731
Year: Issue:  11
Journal: Chinese Journal of Experimental Surgery

Keyword:  Nail matrix naevusGlutathione S transferase M1Glutathione S transferase T1;
Abstract: 目的 探讨谷胱苷肽S转移酶M1(GSTM1)、谷胱苷肽S转移酶T1(GSTT1)基因缺失与甲母痣恶变之间的关系.方法 采用聚合酶链反应(PCR)技术检测77例甲母痣恶变患者和107例甲母痣患者中GSTM1、GSTT1基因缺失的频率.结果 病例组GSTM1基因缺失的频率为58.4%,显著高于对照组的缺失频率42.1%(x2=4.811,P<0.05),危险度分析得出OR=1.938,95%CI为1....
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