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Issue:
Expression and clinical significance of HSP90 and IGF-1R in pancreatic carcinoma
Author(s):
LI Liang
,
LIU Jian-sheng
,
LI Chun-xiao
Pages:
2247
-
2248
Year:
2009
Issue:
12
Journal:
China Tropical Medicine
Keyword:
HSP90
;
胰岛素样生长因子-1受体
;
Abstract:
目的 探讨热休克蛋白90(HSP90)和胰岛素样生长因子-1受体(IGF-1R)在胰腺癌中表达与胰腺癌生物学特性间的相互关系.方法 应用免疫组织化学Envision两步法检测45例胰腺癌组织及20例癌旁正常组织中HSP90和IGF-1R的表达情况.结果胰腺癌组织中HSP90与IGF-1R表达率分别为73.3%(33/45)、62.2%(28/45),显著高于癌旁正常胰腺组织的表达20%(4/20)...
Citations
Therapeutic and diagnostic implications of Hsp90 activation
Kamal A.Boehm MF.Burrows FJ
肺癌癌基因蛋白产物同步检测的对比分析
赵彤.朱梅刚.黄宗义
Circulating insulin-like growth factor Ⅰlevels regulatecolon cancer growth and metastasis
Wu Y.akar S.Zhao L
High HSP90 expression is associated with decreased survival in breast cancer
PickE.KlugerY.Giltnane JM
Effect of Hsp90 inhibition on Rac activation,cell migrstion,tumor growth and liver matastasis of human pancreatic carcinoma
Todd w Bauer.Ray J Somcio.Anthony D Yang
Insulin-like growth factor 1 induces adhesion and migration in human mutiplemyeloma cells via activatio of beta 1 integrin and phasphatidylinositol 3'integrin and phosphatidylinositol 3'kinase/AKT signaling
TaiY T.PodarK.Catkey L
Regulation of hipoxia-reducibal factor lalfa,vasculial endothelial growth factor and angeogenesis by a insulin-like growth factor1 receptor in auto crine loop in human pancreatic cancer
Stoeltzing O.Liu W Reinmuth
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