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Research progress of mechanism of the cortical reaction in mammalian eggs
Author(s): 
Pages: 27-30
Year: Issue:  8
Journal: Heilongjiang Animal Science and Veterinary Medicine

Keyword:  皮质颗粒Ca2+释放三磷酸肌醇蛋白激酶C;
Abstract: 卵子皮质反应是涉及因素较多且非常重要的细胞事件,是受精过程中阻止多精授精重要机制之一,因此是受精生物学、发育生物学、生殖生物学、生殖生理学等学科的重要内容之一.在皮质反应中涉及信号转导和级联反应机制,即皮质颗粒如何形成、迁移、胞吐;精子如何诱发卵子激活;Ca2+如何产生及诱导释放,以上事件均是在蛋白激酶C的调节下进行的.笔者主要从皮质反应的概念及其作用,皮质颗粒的受体控制假说和精子因子假说、Ca2...
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