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Progress in study on cause of pre-eclampsia
Author(s): 
Pages: 679-681
Year: Issue:  5
Journal: Chinese Journal of Woman and Child Health Research

Keyword:  子痫前期病因学分子生物学多因素疾病;
Abstract: 子痫前期是围产期母婴死亡的主要原因之一,通常发生在孕中晚期,病情变化复杂很难预知,一般以终止妊娠来控制病情发展.其病因和发病机理目前尚不清楚,可能与妊娠期间胎盘缺血缺氧、脂代谢异常、免疫失衡、基因调节失控、线粒体缺陷和细胞滋养层细胞侵入子宫内膜有关.子痫前期和子痫是多因素疾病,可能是环境的危险因素与体内一个或多个易感基因协同作用的结果 .胎盘肾素血管紧张素系统和人类组织相溶性抗原的表达起了明显作用...
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