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Protective effect of alanyl-glutamine dipeptide on acute gastric ulcer in rats
Author(s): 
Pages: 372-376
Year: Issue:  5
Journal: International Journal of Pharmaceutical Research

Abstract: 目的 在急性胃溃疡大鼠模型上评价丙氨酰谷氨酰胺二肽预防给药对不同因素所致大鼠急性胃溃疡的作用,探讨其可能作用机制.方法 建立水浸应激、无水乙醇和幽门结扎所致急性胃溃疡大鼠模型.每种胃溃疡模型均选用60只SD大鼠,随机分为模型组、西咪替丁(0.1 g/kg)组、麦滋林-S(1.0 g/kg)组以及丙氨酰谷氨酰胺二肽低(0.5 g/kg)、中(1.0 g/kg)及高(1.5 g/kg)剂量组.实验前分...
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