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The relationship of hepatoma-derived growth factor with metastasis of bladder carcinoma and its influence on invasiveness of T24 cells
Author(s): ZHANG Hui, SHANG Chao, SONG Yongsheng
Pages: 402-
404
Year: 2010
Issue:
5
Journal: Progress of Anatomical Sciences
Abstract: 目的 探讨肝癌衍生生长因子(HDGF)基因与膀胱癌转移的相关性,及其稳定表达对膀胱癌细胞侵袭能力的影响.方法 应用荧光定量PCR检测原发未转移膀胱癌和原发伴转移膀胱癌组织中HDGF mRNA的表达.设计并合成HDGF特异性的siRNA,转染膀胱癌T24细胞系,检测转染后细胞侵袭能力的变化.结果 原发伴转移膀胱癌组织中HDGF mRNA表达较原发未转移膀胱癌中明显上调(P<0.05).RNA干扰后,...
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