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Relationship between plasma level of leptin and the expression of leptin receptor in human adrenal tissues and tumors
Author(s): CHEN Shi, ZENG Zhengpei, LI Hanzhong, TONG Anli, LU Lin, SONG Ailing, LI Ming, LIANG Wei, MAN Na, CAO Caixia
Pages: 2667-
2670
Year: 2010
Issue:
38
Journal: National Medical Journal of China
Keyword: Adrenal gland neoplasms; Leptin; Leptin receptor;
Abstract: 目的 观察长型瘦素受体(Ob-Rb)在正常肾上腺皮、髓质及其肿瘤中的mRNA和蛋白表达;并观察原发性醛固酮增多症(PA)、皮质醇分泌瘤(CS)和嗜铬细胞瘤(PHEO)患者的血浆瘦素水平.方法 提取6名健康者肾上腺皮质和髓质和10例CS、14例醛固酮分泌瘤(APA)、20例PHEO患者的组织总RNA和蛋白,用反转录-聚合酶链反应(RT-PCR)和Western印迹法检测不同组织中Ob-Rb mRNA...
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