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mei duo ba dui pa jin sen bing bing ren tong xing ban zuo an suan de ying xiang
Pages: 1188-1189
Year: Issue:  10
Journal: Research of Traditional Chinese Medicine

Keyword:  帕金森病 同型半胱氨酸 美多巴;
Abstract: 目的探讨美多巴对帕金森病(PD)病人血浆同型半胱氨酸(Hcy)、叶酸及维生素B12浓度的影响。方法检测17例PD病人美多巴治疗前后及35名健康对照者的血浆Hcy、叶酸及维生素B12水平。结果 PD组治疗后Hcy水显著高于治疗前及健康对照组(P<0.05);PD组治疗前后血浆叶酸及维生素B12浓度无统计学意义(P>0.05)。经多元线性回归分析PD组美多巴治疗前的血Hcy水平与叶酸呈负相关(r=0.692,P=0.015)。结论美多巴可以引起高Hcy血症,其机制并非通过影响体内叶酸及维生素B12的含量。
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