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tou di wei yu zhi you dao da shu nao que xue nai shou de yan jiu
Author(s): 
Pages: 1218-1219
Year: Issue:  10
Journal: Research of Traditional Chinese Medicine

Keyword:  头低位 脑缺血 脑保护 动物模型;
Abstract: 目的建立可重复性局灶大鼠脑缺血模型,研究头低位预置对大脑中动脉闭塞的影响。方法采用线栓法建立局灶性脑缺血模型。术后24h检测神经功能缺失评分;TTC染色测量梗死范围;HE染色对梗死周边区损伤神经元的半定量分析。结果术后24h,头低位(H)组、药物(D)组与对照(N)组相比,神经功能明显改善,梗死周边区脑组织的缺血性损伤明显减轻,脑梗死体积明显缩小,而H组和D组间差异无统计意义。结论头低位预置对随后的脑缺血产生了保护作用。
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