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Significance of Expressions of BAK and BAG-1 Proteins in Colorectal Carcinoma
Author(s): 
Pages: 755-757,766
Year: Issue:  7
Journal: Chinese Journal of Biologicals

Keyword:  结直肠肿瘤bcl-2同源拮抗杀伤蛋白质BAG-1蛋白免疫组织化学;
Abstract: 目的 探讨BAK和BAG-1蛋白在结直肠癌中的表达及其意义.方法 采用免疫组化SP法对80例结直肠癌、40例结直肠腺瘤及25例癌旁正常结直肠黏膜组织中BAK和BAG-1蛋白的表达进行检测,并分析其与结直肠癌临床病理特征之间的相关性.结果 BAK和BAG-1蛋白在结直肠癌中过度表达,表达率分别为72.5%(58/80)和80%(64/80),且BAG-1蛋白与肿瘤的分化程度呈负相关,BAK蛋白与肿瘤...
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