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Inhibitory Effect of L-Arginine on Cardiomyocyte Hypertrophy Induced by High Glucose and Insulin
Author(s): 
Pages: 692-695
Year: Issue:  7
Journal: Chinese Journal of Biologicals

Abstract: 目的 探讨L-精氨酸(L-Arg)对高糖高胰岛素(High glucose and insulin,HGI)诱导心肌细胞肥大的抑制作用.方法 体外培养乳鼠心肌细胞,将细胞分为正常对照组(5.5 mmol/L葡萄糖)、模型组(HGI组,给予25.5 mmol/L葡萄糖与0.1μmol/L胰岛素)、L-Arg低、中、高剂量组(给予HGI组药物,并分别加入0.01、0.1和1.0 mmol/L的L-Ar...
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