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Expression of Kidney Injury Molecule-1 in Rat Model of Acute Kidney Injury Induced by Gentamycin
Author(s): 
Pages: 700-703
Year: Issue:  7
Journal: Chinese Journal of Biologicals

Abstract: 目的 探讨庆大霉素(Gentamycin,GM)诱导急性肾损伤大鼠模型肾损伤分子-1(Kidney injury molecule-1,KIM-1)的表达.方法 建立GM诱导大鼠急性肾损伤模型;检测各组大鼠血、尿各项生化指标;取大鼠肾组织,进行病理组织学观察;ELISA法检测各组大鼠尿液中KIM-1的分泌;RT-PCR法检测各组大鼠肾组织KIM-1 mRNA的表达;免疫组织化学SP法检测各组大鼠肾...
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