Expression of nuclear factor- κB and its regulated cytokines in dendritic cells in patients with chronic severe hepatitis B and its clinical significance
Author(s): QIAN Zhi-ping, LI Ning, ZHU Meng-qi, ZHENG Jian-ming, ZHANG Yu-jie, LI Qian, CHEN Ming-quan, WANG Jie-fei, SHI Guang-feng
Pages: 590-594
Year: 2010 Issue: 8
Journal: Chinese Journal of Hepatology
Keyword: Hepatitis B; chronic; Cytokines; Dendritic cells; Nuclear factor kappa B;
Abstract: 目的 探讨慢性乙型重型肝炎(CSHB)患者外周血单个核细胞衍生的树突状细胞核因子(NF)-κB、肿瘤坏死因子(TNF)α、白细胞介素(IL)-6与疾病严重程度及预后的相关性.方法 采集37例CSHB患者、20例慢性乙型肝炎(CHB)患者和20例健康对照者的外周血,分为CSHB组、CHB组与对照组并分别用密度梯度离心法分离外周血单个核细胞,用免疫磁珠细胞分选法获得纯化的单核细胞,体外培养6 d为未成...
Pages: 590-594
Year: 2010 Issue: 8
Journal: Chinese Journal of Hepatology
Keyword: Hepatitis B; chronic; Cytokines; Dendritic cells; Nuclear factor kappa B;
Abstract: 目的 探讨慢性乙型重型肝炎(CSHB)患者外周血单个核细胞衍生的树突状细胞核因子(NF)-κB、肿瘤坏死因子(TNF)α、白细胞介素(IL)-6与疾病严重程度及预后的相关性.方法 采集37例CSHB患者、20例慢性乙型肝炎(CHB)患者和20例健康对照者的外周血,分为CSHB组、CHB组与对照组并分别用密度梯度离心法分离外周血单个核细胞,用免疫磁珠细胞分选法获得纯化的单核细胞,体外培养6 d为未成...
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