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Experimental study on emergency management of shock due to heatstroke
Author(s): HUA Xu-chu, ZOU Fei, WANG Dao-xuan, LAO Hai-miao, LOU Bing-deInstitute of Tropical Medicine, Cursing Department, Nanfang Hospital, First Military Medical University, Guangzhou 510515, China
Pages: 5-
7
Year: 2001
Issue:
S1
Journal: Journal of Southern Medical University
Keyword: GetLinkList(KeywordFilter('中暑; 休克; 腹腔灌洗; 盐酸山莨菪碱'); 'kw'; 'CJFD');
Abstract: 为了探讨中暑休克的抢救方法,将家兔热暴露至休克发生,然后将其置于室温下。用不同方法抢救后,观察动物中心体温的变化和存活时间。(1)对照组(n=7),在室温下自然冷却,直肠温度(Tr)和食道温度(Te)不降或略升,全部动物在几分钟内死亡,平均存活(7.57±3.11)min;(2)冷水浸泡组(n=6),Tr和Te下降缓慢,平均存活(14.00±23.27)min;(3)腹腔冷液灌洗组(n=8),平均存活(83.00±65.68)min;(4)药物腹腔灌洗组(n=9),在腹腔灌洗液中加入山莨菪碱,平均存活(89.89±35.78)min。两个腹腔灌洗组都使Tr和 Te下降迅速,血压回升,比对照组和冷水浸泡组存活时间显著延长,30min存活率显著提高,但药物灌洗组与单纯腹腔泠液灌洗组尚无统计学差异。结果提示,腹腔冷液灌洗是抢救中暑休克有效的方法,为进一步救治赢得了时间。
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