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Effects of Ovarian Development by P450 Aromatase Activity Controled in Mice
Author(s): 
Pages: 95-100
Year: Issue:  8
Journal: China Animal Husbandry & Veterinary Medicine

Keyword:  小鼠卵巢P450芳香化酶来曲唑;
Abstract: 本研究旨在探索P450芳香化酶抑制剂(来曲唑)对小鼠卵巢发育的影响.将SPF级昆明系雌性小鼠随机分为对照组和2、4、6、8、10、30、50 g/kg来曲唑剂量组,连续灌服3 d,在停药后的第9、15和30天观测小鼠卵巢的发育情况.结果表明:①在停药后第9、30天的6和8 g/kg组及第15天的4~10 g/kg组的卵巢指数显著高于对照组(P<0.05),而停药后第15和30天的50 g/kg组显...
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