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Differentiation of rat bone marrow stromal cells into neural stem cells induced by baicalin in vitro
Author(s): 
Pages: 5054-5057
Year: Issue:  27
Journal: Journal of Clinical Rehabilitative Tissue Engineering Research

Abstract: 背景:已有实验表明,骨髓基质细胞具有分化为骨骼、神经干细胞及造血干细胞的巨大潜能,而黄芩甙具有诱导细胞分化的作用.目的:探讨黄芩甙体外诱导骨髓基质细胞分化为神经干细胞的可能性.方法:分离培养Wistar纯系大鼠骨髓基质细胞,并将分离的骨髓基质细胞分为实验组和对照组,对照组不干预,实验组用黄芩甙(350-400 μmol/L)诱导,2组的培养环境相同.持续诱导6 d后选取生长良好的细胞进行蛋白质印迹...
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