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Comparative study on the proliferation and invasion of two esophageal squamous carcinoma cell lines
Author(s): XIE Yangmin, DONG Hui, XIE Jianjun, WU Zhiyong, DU Zepeng, LI Liyan, XU Xiue, ZHOU Fei, CHEN Tao, SHI Hongshun, XU Liyan, LI Enmin
Pages: 261-
264
Year: 2010
Issue:
4
Journal: Carcinogenesis,Teratogenesis and Mutagenesis
Keyword: 食管癌细胞; 细胞增殖; 细胞侵袭; 转移;
Abstract: 目的:研究两种来源不同的食管鳞癌细胞系EC109和KYSE510分裂增殖能力和侵袭能力的差异.方法:利用MTT实验和侵袭实验,在体外分别检测EC109和KYSE510细胞的分裂增殖能力和侵袭能力;采用裸鼠皮下接种实验和爪垫皮下接种淋巴结转移模型,比较两种细胞在体内的成瘤能力、局部侵袭能力和区域淋巴结转移能力的差异;免疫印迹检测上皮-间充质细胞转换标志蛋白E-cadherin、γ-cadherin和...
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