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Issue:
Anti-cancer effects of immunotoxins and its improvement strategy
Author(s):
XU Wei
Pages:
419
-
422
Year:
2010
Issue:
6
Journal:
Journal of International Oncology
Keyword:
Immunotoxins
;
Neoplasms
;
Therapy
;
Abstract:
免疫毒素由特异性的单克隆抗体或生长因子与具有杀伤作用的毒素分子通过化学交联构建而成.它通过抑制癌细胞的蛋白合成或促进癌细胞凋亡发挥抗癌作用.与其他抗肿瘤药物相比,具有毒性强和特异性高的优点,在肿瘤治疗中显示出巨大的应用前景.但进入临床应用还存在很多限制性因素.
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