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Expression of the platelet extract's neuropeptide and neurotensin in hemodialysis
Author(s): LUO Nanping, YANG Daoli, MENG Jianzhong, WU Cuihua, QI Falian, KONG Lixin, LIU Wenyuan
Pages: 283-
284
Year: 1999
Issue:
6
Journal: CHINESE JOURNAL OF IMMUNOLOGY
Keyword: 神经肽Y; 神经降压素; 血小板; 血浆; 血液透析;
Abstract: 目的:探讨血液透析(HD)过程血小板中神经肽Y(NPY)与神经降压素(NT)的含量变化及意义.方法:HD患者35例,对照组30例.采用放射免疫分析法测定血小板提取液和血浆中NPY及NT的含量.结果:与对照组比较,HD患者血小板提取液NPY含量明显降低,血浆中NPY含量明显增高,血小板提取液与血浆NT含量均显著升高.与HD前比较,HD后血浆NT与血小板NPY均明显增高,血小板中NT与血浆NPY明显降低,两者具有显著相关性.结论:在HD过程中,血小板释放的NPY可能是造成肾性高血压和肾血管痉挛的重要病理因素.
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