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Effect of Yazhoukangtai capsule on alveolar bone of experimental periodontitis
Author(s): LIU Ailian1, WANG Guofang2, ZHANG Jie2, WANG Shouru2(1thefirstaffiliatedhospitalofzhengzhouuniversity, ZHENGZHOU 450052, china, 2 Henancollegeoftraditionalchinesemedicine, ZHENGZHOU 450002, china)
Pages: 1336-
1339
Year: 2004
Issue:
S1
Journal: Chinese Journal of New Drugs
Keyword: 牙周炎; 牙周康泰胶囊; 牙槽骨; 大鼠;
Abstract: 目的:观察牙周康泰胶囊对实验性牙周炎牙槽骨的影响。方法:采用泼尼松龙加结扎法建立牙周炎大鼠模型,将50只wistar大鼠随机分为正常组、模型组、牙周宁对照组、牙周康泰高低剂量组,每组10只。连续用药8周,于用药第0,1,2,4和8周各组随机取2只动物处死,拍上下颌骨软射线片,并做病理切片。观察动物的一般状况,牙槽骨吸收情况,以及牙周组织病理学变化,并测量牙槽骨高度。结果:牙周康泰高、低剂量组大鼠用药后全身症状很快得到改善,牙槽骨高度在用药4周以后均高于模型组(P<0.05
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