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Issue:
Microarray analysis of gene expression profiles in pelvic organ prolapse
Author(s):
DAI Zuoxin
,
LANG Jinghe
,
ZHU Lan
,
LIU Zhufeng
,
PAN Lingya
,
SUN Dawei
Pages:
342
-
347
Year:
2010
Issue:
5
Journal:
Chinese Journal of Obstetrics and Gynecology
Keyword:
Uterine prolapse
;
Oligonucleotide array sequence analysis
;
Intercellular signaling peptides and proteins
;
Membrane proteins
;
Neurodegenerative diseases
;
Abstract:
目的 应用基因表达谱芯片检测绝经后盆腔器官脱垂(POP)患者与绝经后非POP患者子宫主韧带组织中差异表达的基因,探讨POP发生的分子机制.方法 选择2007年1-5月在北京协和医院妇产科手术的绝经后POP患者3例为POP组,同期因妇科良性疾病行子宫全切除术的绝经后非POP患者3例为对照组.获取两组患者的子宫主韧带组织,进行组织来源确定及形态学观察;应用基因表达谱芯片筛选两组子宫主韧带组织中的差异表...
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