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Microarray analysis of gene expression profiles in pelvic organ prolapse
Author(s): 
Pages: 342-347
Year: Issue:  5
Journal: Chinese Journal of Obstetrics and Gynecology

Keyword:  Uterine prolapseOligonucleotide array sequence analysisIntercellular signaling peptides and proteinsMembrane proteinsNeurodegenerative diseases;
Abstract: 目的 应用基因表达谱芯片检测绝经后盆腔器官脱垂(POP)患者与绝经后非POP患者子宫主韧带组织中差异表达的基因,探讨POP发生的分子机制.方法 选择2007年1-5月在北京协和医院妇产科手术的绝经后POP患者3例为POP组,同期因妇科良性疾病行子宫全切除术的绝经后非POP患者3例为对照组.获取两组患者的子宫主韧带组织,进行组织来源确定及形态学观察;应用基因表达谱芯片筛选两组子宫主韧带组织中的差异表...
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