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Issue:
Expression of VEGF and its mechanism of invasion in gastric carcinoma
Author(s):
LIAN Peilong
,
ZHAO Rui
,
LIU Yanfeng
,
MA Haichang
,
XU Kesen
Pages:
184
-
187
Year:
2010
Issue:
3
Journal:
Chinese Journal of Current Advances in General Surgery
Abstract:
目的:探讨血管内皮生长因子(VEGF)在胃癌组织中的表达及其对基质金属蛋白酶-9(MMP-9)的表达的影响在胃癌侵袭机制中的意义.方法:采用免疫组织化学法、MTT法、实时定量PCR及Western blot,观察胃癌组织及癌旁组织中VEGF的表达、VEGF对胃癌AGS细胞增殖和AGS细胞中MMP-9 mRNA及蛋白表达的影响.结果:VEGF在胃癌中高表达;经VEGF刺激后,AGS细胞增殖明显,MM...
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