Author(s): CUI Wenyu, NIE Hongjing, ZHANG Dongxiang, XIAO Zhonghai, ZHANG Yanfang, CUI Jianhua, SHI Yongping, LONG Chaoliang, WANG Yinhu, WANG Hai
Pages: 190-193
Year: 2010 Issue:  2
Journal: Chinese Journal of Clinical Pharmacology and Therapeutics
Keyword:  Deacclimatization to high altitude; ATP-sensitive potassium channel opner; Iptakalim;
Abstract: 目的:观察长期口服埃他卡林对高原脱习服的影响.方法:该临床研究采用随机双盲安慰剂平行对照试验方法,随机分为埃他卡林试验组和安慰剂对照组,两组受试者分别为39例和17例.其中,受试者分别口服埃他卡林片(5 mg/片,1次/日)或安慰剂(1片/日),连续服用药物7个月,下山到3700 m停留2 d并停止服药,再返回到海拔1400 m的平原地区,自返回平原的第2、4、6天,进行高原脱习服症状调查,随访受...