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Influence of Cardiac Pacemaker Implantation Site on Plasma Tumor Necrosis Factor
Author(s): 
Pages: 536-538
Year: Issue:  5
Journal: Research of Traditional Chinese Medicine

Keyword:  右心室间隔部起搏 右心室心尖部起搏 肿瘤坏死因子TNF-α;
Abstract: 目的比较右心室心尖部(RVA)和右心室间隔部(RVS)不同部位起搏早期对患者血浆肿瘤坏死因子(TNF-α)水平的影响。方法将25例植入DDD型起搏器患者随机分为3组,RVA起搏组、RVS起搏组、对照组,对比观察3组患者植入起搏器前及术后3个月血浆TNF-α的变化。结果术前3组患者血浆TNF-α水平比较差别无统计学意义(P>0.05);术后一周3组患者血浆TNF-α水平两两比较差别无统计学意义(P>0.05);术后3月RVA起搏组与术前、术后一周比较TNF-α水平,差别有统计学意义(P<0.001),即RVA起搏组患者血浆TNF-α水平随时间增加而增加;RVS起搏组较术前、术后一周TNF-α水平比较,差别无统计学意义(P>0.05);RVA起搏组较RVS起搏组TNF-α水平升高,差别有统计学意义(P<0.001)。结论右心室间隔部起搏较右心室心尖部起搏更有利于双心室电激动的同步性,且对心功能的影响较小,右心室间隔部起搏是安全、有效的。
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