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Study on the rat model for the influence of isoflurane on aged spatial memory
Author(s): 
Pages: 695-697
Year: Issue:  5
Journal: The Journal of Practical Medicine

Keyword:  异氟醚放射状迷宫记忆障碍老龄大鼠;
Abstract: 目的:建立一种有效评价异氟醚对老龄大鼠空间记忆影响的动物实验模型.方法:共24只18~22月龄雄性Wistar老龄大鼠经放射状八臂(四臂放食物)迷宫训练成功后,随机分为对照组和麻醉组,每组12只.对照组吸入70%空气和30%氧气2 h,麻醉组在此基础上吸入1.5%异氟醚2 h.麻醉完全苏醒24 h后,在同一迷宫测试空间记忆的再现过程,连续测试1周,记录每天工作记忆错误和参考记忆错误.结果:与对照组...
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