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Research progress on long-acting glucagon-like peptide-1 receptor agonists
Author(s): 
Pages: 370-375
Year: Issue:  6
Journal: World Clinical Drugs

Keyword:  胰高血糖素样肽-1受体激动剂2型糖尿病;
Abstract: 新型2型糖尿病治疗药物胰高血糖素样肽-1(GLP-1)受体激动剂与传统降糖药物相比,具有促β细胞增生、稳定患者血糖水平和减轻体重等特点.通过对GLP-1及其类似物exendin-4进行结构修饰已获得一系列长效GLP-1受体激动剂.本文基于对GLP-1受体及其受体结构和功能的认识,对长效GLP-1受体激动剂的研究进展进行综述.
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