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Effects of atorvastatin on the number of circulating endothelial progenitor cells and myocardial neovascularization in rabbits
Pages: 115-119
Year: Issue:  2
Journal: Pharmaceutical Care and Research

Abstract: 目的:观察兔心肌梗死模型中不同剂量阿托伐他汀对循环内皮祖细胞数量和心肌血管新生的影响.方法:建立新西兰大耳白兔心肌梗死模型后,动物随机分成生理盐水[5 mg/(kg·d)]对照组、阿托伐他汀常规剂量组[5 mg/(kg·d)]和阿托伐他汀强化剂量组[20 mg/(kg·d)],灌胃给药8周.取外周血分离单核细胞进行内皮祖细胞培养1周后,鉴定FITC-UEA-Ⅰ和Di1-acLDL双染色阳性细胞为正...
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