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Study on the Labeling Conditions of 99TCm (CO)3.-C60 (OH)20 and Its in vitro Behavior
Author(s): 
Pages: 6-10
Year: Issue:  1
Journal: Journal of Southwest University of Science and Technology

Abstract: 以99TcmO4-淋洗液为起始物,在0.1 MPa CO条件下成功制备了羰基锝中间体[99Tcm(CO)3(H2O)3]+,并研究了反应体系pH值、配体C60(OH)20浓度以及反应温度和时间对99Tcm(CO)3-C60(OH)20配合物标记率的影响,测定了该配合物的脂水分配系数并观测了其在体外的稳定性和抗稀释稳定性.结果表明,该配合物的最佳标记条件为:0.1 mL[99Tcm(CO)3(H2O...
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