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Location of the major cell surface protein antigen of streptococcus sobrinus with monoclonal antibody by immunogold electron microscope.
Author(s): 
Pages: 134-137
Year: Issue:  3
Journal: JOURNAL OF COMPREHENSIVE STOMATOLOGY

Keyword:  单克隆抗体表面蛋白抗原茸毛链球菌;
Abstract: 目的:研究所制备的单抗与其相应的非变性抗原PAg的反应,并直观显示PAg在茸毛链球菌原位的分布.方法:采用间接免疫金标技术,通过透射电镜观察,并设置多抗以及变形链球菌和鼠链球菌作为对照.结果:抗PAg的单抗可与茸毛链球菌发生反应,与变形链球菌反应不明确,与鼠链球菌不发生反应.结论:所制备的单抗能与PAg特异性结合,PAg可能与茸毛链球菌表面茸毛层相关.
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