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Immune effect of polyvalent inactived vaccine against swine Streptococcus on experimental mice
Pages: 8-10
Year: Issue:  4
Journal: Liaoning Journal of Animal Husbandry and Veterinar

Keyword:  猪链球菌 多价灭活疫苗 安全性 免疫效力 实验小鼠;
Abstract: 临床分离的猪链球菌经随机扩增多态性DNA分析,挑选出4株毒力强、免疫原性好且遗传距离较远的猪链球菌作为疫苗株,研制出猪链球菌病氢氧化铝胶多价灭活疫苗。该疫苗对实验小鼠安全性好,无不良反应。实验室的小鼠免疫效力试验证实该苗的保护率为100%,优于单价灭活疫苗和猪链球菌病活疫苗。
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