Author(s): ZHAO Yanmin, YANG Jinhui, XIAO Dongcai, WANG Wei, TIAN Lili
Pages: 10-12,103
Year: 2010 Issue:  1
Journal: Chinese Journal of Synthetic Chemistry
Keyword:  (±)-Abyssinone Ⅰ; flavanone; isoprenyl flavanone; total synthesis;
Abstract: 以对羟基苯甲醛和2,4-二羟基苯乙酮为起始原料,经过C-异戊烯基化、选择性的保护酚羟基、羟醛缩合、催化环化、去保护基等步骤,以25%的总收率首次完成了天然产物(±)-Abyssinone Ⅰ(1)的全合成.其中新化合物4,7,8和1的结构经~1H NMR,IR和MS表征.