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Issue:
Antimicrobial Activity and Mechanism of Flavonoids
Author(s):
XUAN Hongzhuan
,
HU Fuliang
Pages:
171
-
175
Year:
2010
Issue:
1
Journal:
Natural Product Research and Development
Keyword:
flavonoids
;
antifungal
;
antiviral
;
antibacterial
;
structure-activity
;
Abstract:
本文综述了黄酮类化合物抑制细菌、病毒和真菌的活性及可能的作用机制,黄酮类化合物结构与抑菌活性之间的关系.结果表明,黄酮类化合物主要通过抑制细菌DNA旋转酶,抑制细菌细胞质膜的功能,抑制细菌能量代谢等方面发挥抑菌功效.指出黄酮类化合物是今后抗病源微生物药物开发新的研究方向.
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