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Significance of high dose methylprednisolone in the treatment of severe hand-foot-mouth disease
Author(s): 
Pages: 106-108,112
Year: Issue:  3
Journal: Acta Academiae Medicinae Shandong

Keyword:  Handfoot and mouth diseaseEnterovirus-71GlucocorticoidClinical research;
Abstract: 目的探讨大剂量甲泼尼龙冲击治疗重症手足口病的疗效。方法按是否应用大剂量甲泼尼龙冲击治疗,将重症手足口病患儿分为激素冲击组和非激素冲击组,然后对其相关临床信息进行比较分析。结果两组患儿在发热持续时间、神经系统受累持续时间、住院时间、血压、治愈率等方面比较差异无统计学意义(P>0.05);而大剂量激素冲击组患儿的心率、呼吸频率、血糖均数明显高于非激素冲击组,差异具有统计学意义(P<0.05)。结论大剂量激素冲击治疗重症手足口病不能缩短其病程、改善其预后;目前不支持大剂量激素冲击对重症手足口病的疗效。
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