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Role of sipulin injection in comprehensive treatment of lung cancer in medium and terminal stages
Author(s): 
Pages: 113-115,119
Year: Issue:  3
Journal: Acta Academiae Medicinae Shandong

Keyword:  Lung cancer in medium and terminal stagesChemotherapyRadiotherapySipulin injection;
Abstract: 目的观察斯普林注射液配合放、化疗治疗中晚期肺癌的疗效。方法将147例中晚期肺癌患者随机分为斯普林注射液配合放、化疗组(治疗组,75例),单纯放、化疗组(对照组,72例),两组放、化疗方法相同,治疗组在放、化疗开始即给予斯普林10mL,加入0.9%氯化钠注射液250mL中静滴,连用14d,21d为1周期,共4~6周期,对多个临床指标进行比较观察。结果治疗组近期疗效为60.0%,对照组为48.6%,两组无统计学差异(P>0.05)。治疗组1、2年生存率分别为58.9%、41.1%,对照组分别为42.3%、25.4%,两组有统计学差异(P<0.05)。治疗组患者的生活质量、治疗后T细胞亚群及NK细胞活性明显高于对照组,血液学各项指标下降程度、消化道不良反应及放射性食管炎均明显轻于对照组,两组有统计学差异(P<0.05)。结论斯普林注射液用于配合放、化疗治疗中晚期肺癌有一定疗效。
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