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Comparison of the effects of two doses of epinephrine during cardiopulmonary resuscitation in a swine model of prolonged ventricular fibrillation
Author(s): 
Pages: 32-35
Year: Issue:  4
Journal: Acta Academiae Medicinae Shandong

Keyword:  EpinephrineProlonged ventricular fibrillationCardiopulmonary resuscitation;
Abstract: 目的比较两种剂量肾上腺素在长时程室颤家猪心肺复苏中的疗效。方法将16头家猪随机分为两组,分别为标准剂量肾上腺组(0.02mg/kg),大剂量肾上腺组(0.1mg/kg)。采用体外电击法制备室颤动物模型,并于8min室颤后依次给予2min心肺复苏,除颤,肾上腺素。观察血流动力学和自主循环恢复情况。结果自主循环恢复率两组一样,两组间血流动力学和除颤成功率差异无统计学意义。结论大剂量肾上腺素没有改善血流动力学,也没有提高除颤成功率和自主循环恢复率。
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