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Effects of Aspart 30 for new type 2 diabetes
Author(s): 
Pages: 160-161,164
Year: Issue:  4
Journal: Acta Academiae Medicinae Shandong

Keyword:  Diabetesmellitusnon-insulin-dependentIntensive treatmentAspart 30β-cell function;
Abstract: 目的观察初诊2型糖尿病患者经诺和锐30特充强化治疗后胰岛β细胞功能的变化。方法对55例初诊为2型糖尿病的患者进行为期2周的诺和锐30特充治疗,每日3次皮下注射,分析治疗前后口服葡萄糖耐量试验(OGTT)时空腹血糖(FPG)、糖负荷后血糖(PPG)、胰岛素、C-肽、胰岛素及C-肽曲线下面积、胰岛素抵抗指数(HOMA-IR)、胰岛素分泌指数(HOMA-B)等指标的变化。结果短期诺和锐30特充强化治疗后,FPG、PPG较治疗前明显下降(P<0.01),胰岛素、C-肽、胰岛素及C-肽曲线下面积、HOMA-B较治疗前明显升高(P<0.01),HO-MA-IR较治疗前明显下降(P<0.05)。总胆固醇、甘油三脂治疗前后差异无统计学意义(P>0.05)。结论短期诺和锐30特充强化治疗可迅速降低血糖,改善胰岛β细胞功能,减轻胰岛素抵抗。
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