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Effects of hemodilution combined with preemptive analgesia on haemodynamics in free tissue graft
Author(s): 
Pages: 153-156
Year: Issue:  2
Journal: Acta Academiae Medicinae Shandong

Keyword:  HemodilutionTissue graftBlood circulationHypercoagulabilityNorepinephrine;
Abstract: 目的探讨血液稀释联合超前镇痛对移植组织血流动力学影响。方法选择胫骨前软组织缺损采用股前外侧皮瓣修复患者160例,按照麻醉方法随即分为4组,A组:血液稀释联合超前镇痛,B组:血液稀释,C组:超前镇痛,D组:对照组。动态监测手术前后血小板计数、皮质醇、血清去甲肾上腺素含量、部分凝血酶时间、凝血酶原时间、并观察各组皮瓣血管危象发生及皮瓣成活率。结果术前各组指标差异无统计学意义;A组手术前后各指标间差异无统计学意义;B组术后皮质醇、APTT及PT显著增高;C组PLT、HCT显著增高,而皮质醇、血清去甲肾上腺素含量增高差异无统计学意义;D组变化同B组。血管危象发生率AC>B>D组。结论血液稀释联合超前镇痛可明显改善修复组织的血液循环,提高成活率。
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