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The co-effect of hepatic stimulator substance in combination with adriamycin on the cellular apoptosis of human liver cancer in nude mice
Pages: 3767-3770
Year: Issue:  22
Journal: The Journal of Practical Medicine

Abstract: 目的:研究肝细胞刺激因子(HSS)与阿霉素(ADM)联合用药对裸鼠肝癌移植瘤细胞的凋亡作用.方法:建立裸鼠肝癌移植瘤模型;将荷瘤裸鼠分组,分别腹腔内注射不同剂量HSS及ADM;4周后解剖取瘤计算抑瘤率;病理组织学检查;采用Annexin V/PI流式细胞分析法检测肝癌细胞凋亡率.结果:与对照组相比,三种剂量联合用药组抑瘤作用明显(P<0.01).HSS组诱导细胞凋亡作用不明显(P>0.05),AD...
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