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The relative bioavailability and bioequivalence of cefradine dispersible tablets which were administrated in two kinds of ways
Pages: 546-550
Year: Issue:  9
Journal: World Clinical Drugs

Abstract: 目的研究健康受试者两种服用方法服用头孢拉定分散片的人体相对生物利用度和生物等效性.方法在12例健康男性受试者中进行标签开放、随机、2×2交叉研究,分别分散后服、吞服头孢拉定分散片0.5 g.采用高效液相色谱(HPLC)法测定血浆中头孢托定浓度.用DAS软件计算人体相对生物利用度并评价生物等效性.结果分散后服、吞服头孢拉定分散片的达峰时间(tmax)分别为(46.3±17.5)和(51.3±21.7...
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