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Clinical applications of caffeine in neonates
Author(s): 
Pages: 518-522
Year: Issue:  9
Journal: World Clinical Drugs

Abstract: 咖啡因是中枢神经系统兴台药,通过刺激呼吸中枢、阻断腺苷受体和改善呼吸肌功能等发挥作用.其具有肺保护作用,可以减低早产儿呼吸暂停的发生危险,提高撇机成功率,同时具有脑保护作用.该药应用时无需常规监测血药浓度,但极早产儿及频繁呼吸暂停、出现中毒症状的患儿仍仃必要定期监测血药浓度.
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