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The expression and significance of ET-l and MMP-1 in oral leukoplakia and leukoplakia canceation tissue
Pages: 599-600,712
Year: Issue:  6
Journal: Experimental and Laboratory Medicine

Keyword:  口腔粘膜白斑内皮素1基质金属蛋白酶-1白斑癌变;
Abstract: 目的 探讨内皮素(ET-1),基质金属蛋白酶-1(MMP-1)在口腔癌变发病机制中的作用和意义.方法 采用免疫组化染色SABC法对人口腔粘膜白斑48例、白斑癌变患者16例及正常口腔粘膜16例的粘膜鳞状上皮细胞ET-1表达进行定量性分析.结果 MMP-1在正常口腔粘膜,粘膜白斑,白斑癌变中表达率分别为25%,72.92%,75%,3组间χ2检验,正常组与白斑组,白斑癌变组均有显著性差异,P<0.05...
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