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Determination of related substances in azithromycin injection by RP-HPLC
Author(s): 
Pages: 1491-1492
Year: Issue:  12
Journal: Anhui Medical and Pharmaceutical Journal

Abstract: 目的 建立注射用阿奇霉素有关物质的新检测方法.方法 采用反相高效液相色谱法检测注射用阿奇霉素中有关物质.液相色谱条件为:以Shim-pack CLC-ODS不锈钢柱(250 mm×4.6 mm,5 μm)为色谱柱,以0.05 mol·L-1K2HPO4-乙腈(40:60)为流动相,流速1.0 ml·min-1,柱温40℃,检测波长215 nm.结果 阿奇霉素有关物质的检测限度为2.5%,阿奇霉素主...
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