Author(s): SUN Haitao, XUE Fushan, LIU Zuopeng, SUN Li, XU Yachao, LIAO Xu, YANG Quanyong, ZHANG Yanming
Pages: 612-615
Year: 2009 Issue:  5
Journal: Acta Academiae Medicinae Sinicae
Keyword:  remifentanil; preconditioning; ischemia-reperfusion injury;
Abstract: 目的 观察瑞芬太尼预处理对心肌缺血-再灌注损伤的影响.方法 将42只成年雄性Wistar大鼠随机分为7组,每组6只:Ⅰ组经尾静脉输注生理盐水(0.1 ml·kg~(-1)·min~(-1))5 min行预处理,重复3次,每次间隔5 min,24 h后实施缺血-再灌注;Ⅱ组除接受与Ⅰ组相同处理外,在生理盐水预处理前10 min静脉注射纳络酮0.1 mg·kg~(-1);Ⅲ、Ⅳ、Ⅴ和Ⅵ组经尾静脉输注瑞...