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The heterogeneity of anti-GBM autoantibodies in sera from patients with anti-GBM disease and its clinical correlation
Author(s): 
Pages: 625-629
Year: Issue:  6
Journal: Journal of Peking University(Health Sciences)

Keyword:  肾小球基底膜自身抗体抗原抗体抗中性白细胞胞质荧光抗体技术间接Glomerular basement membraneAutoantibodiesAntigensAntibodiesantineutrophil cytoplasmicFluorescent antibody techniqueIndirect;
Abstract: 目曲:研究抗肾小球基底膜(glomemlar basement membrane,GBM)病患者血清自身抗体的异质性及其临床病理的相关性.方珐:选取北京大学第一医院肾内科1991年1月至2009年5月收治的有完整临床及肾活检资料的108例抗GBM病患者为研究对象.收集就诊时的血清或血浆置换液用于孵育正常人肾组织冰冻切片行间接免疫荧光检查.隐匿性抗原表位的暴露采用6 mol/L尿素对组织切片进行预处...
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