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Molecular mechanisms of miRNA and their application to drug research
Author(s): 
Pages: 551-556
Year: Issue:  9
Journal: World Clinical Drugs

Abstract: 微小核糖核酸(miRNA)是一类长约19~23个核苷酸的内源性非编码核糖核酸(RNA),与基因的表达调控密切相关.其在生长发育、细胞分化与增生、细胞凋亡、激素分泌、脂肪代谢及癌症的发生发展等生命活动中具有重要作用.miRNA作为潜在的药物开发新靶点引起关注,基于miRNA的分子机制及其在药物研发中的应用值得探讨.
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