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The relationship between Gamma-glutamyl transferase and insulin resistance in patients with diabetic mellitus
Pages: 280-281
Year: Issue:  3
Journal: Qianwei Journal of Medicine & Pharmacy

Keyword:  Diabetic mellitus Gamma-glutamyltransferase Insulin resistance;
Abstract: Objective To study the relationship between Gamma glutamyl transferase(GGT) and insulin resistance in patients with diabetic mellitus.Methods The 102 patients with 2 type diabetic mellitus were selected, and serum levels of fast blood glucose, GGT, triglyceride(TG) and insulin were measured. The insulin resistance index(HOMA-IR) was calculated by the model of HOMA. The 102 patients were divided into high GGT group and normal GGT group by the serum level of GGT.Results HOMA-IR(3.841±2.224) and TG levels(2.70±1.85mmol/l) in high GGT group were higher obviously than those(2.236±1.749,1.49±0.6mmol/l) of normal GGT group, and the differences were significant(t=4.037,4.472, P<0.001).Positive correlation was shown between GGT and HOMA-IR(r=0.189,P>0.05), significant positive correlation was shown between TG and HOMA-IR(r=0.291,P<0.01).Conclusion There is some correlation between serum GGT and insulin resistance in patients with diabetic mellitus, and GGT may be a risk mark of diabetic mellitus.
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