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A Comparative study of patient-controlled epidural analgesia and subcutaneous analgesia for advanced cancer patients in familial-ward
Author(s): 
Pages: 270-272
Year: Issue:  3
Journal: Qianwei Journal of Medicine & Pharmacy

Keyword:  Cancer Patient-controlled analgesia Familial ward;
Abstract: Objective To compare the efficacy and safety of patient-controlled analgesia by either subcutaneous or epidural for advanced cancer patients in familial-ward.Methods Thirty-two patients were randomly allocated to patient-controlled epidural (PCEA) group or patient-controlled subcutaneous(PCSA)group (16 in each group).Group PCEA was given loading dose of 5ml,PCA bolus 0.5ml,background 2ml/h,lockout time 15min.In Group PCSA, patients received 1μg/kg of fentanyl and 0.05mg/kg droperidol by intramuscular injection before using a patient-controlled analgesic (PCA)delivery system. loading dose of 5ml,PCA bolus 0.5ml,background 2kl/h,lockout time 15min.Heart rate,blood pressure,respi-ratory rate,pulse,VAS,sedation score(ss) of the patients as well as adverse reactions were observed.Results Group PCEA was superior to Group PCSA in the analgesia profile in the first 24h;in the other time, there were no distinct differences between the two groups.In the incidence of nausea, flatus passage, urinary retention and part of puncture inflammation, group PCEA was higher than group PCSA. Conclusion There is higher analgesic efficacy in the group PCEA.The group PCSA could be managed with convenience, safety , economy and fewer adverse reactions.
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