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jing mai shu zhu dan xiao suan yi shan li zuo ji xiao suan gan you zhi liao man xing chong xue xing xin li shuai jie de lin chuang guan cha
Author(s): 
Pages: 726-727
Year: Issue:  6
Journal: Research of Traditional Chinese Medicine

Keyword:  单硝酸异山梨酯硝酸甘油心力衰竭充血性;
Abstract: 目的比较单硝酸异山梨酯(ISMN)注射液及硝酸甘油(NTG)治疗慢性充血性心力衰竭(CHF)的有效性及其安全性。方法65例慢性充血性心力衰竭病人随机分为两组,ISMN组(32例)用单硝酸异山梨酯注射液(2040)mg加入5%葡萄糖液250mL中静脉输注,每天1次;NTG组(33例)以(1020)μg/min持续静脉泵入,治疗5d后,比较两组疗效及不良反应发生的情况。结果ISMN组治疗5 d后CHF病人心功能改善的总有效率明显高于NTG组(P<0.05);ISMN组心悸、气短、水肿、肝缩小、肺部口罗音改善时间明显短于NTG组(P<0.05),且和NTG组相比ISMN不良反应少(P<0.05)。结论静脉输注ISMN治疗CHF病人疗效优于NTG持续静脉泵入,副反应小,可作为治疗CHF病人的有效措施之一。
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